• World Neurosurg · Jul 2019

    Case Reports

    Case report of the rarely described polymorphous low-grade neuroepithelial tumor of the young and comparison with oligodendroglioma.

    • Hasan Sumdani, Zanab Shahbuddin, Glenn Harper, and Lesley Hamilton.
    • Seton Medical Center Williamson, Round Rock, Texas, USA. Electronic address: hsumdani@medicine.tamhsc.edu.
    • World Neurosurg. 2019 Jul 1; 127: 47-51.

    BackgroundPolymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a central nervous system tumor that shares many qualities with oligodendroglioma but is rarely and only very recently described as a distinct entity in the literature.Case DescriptionA previously healthy, 19-year-old man presented with new onset of seizures. Imaging showed an intracranial mass, which was treated with surgical removal. Preoperative and postoperative magnetic resonance imaging, histopathologic examination, genetic testing, and immunohistochemical staining all supported a diagnosis of PLNTY.ConclusionsDiagnostic investigation of PLNTY shows many similarities with oligodendroglioma, and thus these entities can be mistaken for one another. Certain studies are needed to distinguish PLNTY and other dysembryoplastic neuroepithelial tumors, such as oligodendroglioma.Copyright © 2019 Elsevier Inc. All rights reserved.

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