• Timothy J Bernard, Neil R Friedman, Nicholas V Stence, William Jones, Rebecca Ichord, Catherine Amlie-Lefond, Michael M Dowling, and Michael J Rivkin.
• Hemophilia and Thrombosis Center, University of Colorado School of Medicine, Aurora, Colorado; Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado. Electronic address: Timothy.Bernard@childrenscolorado.org.
• Pediatr. Neurol. 2016 Mar 1; 56: 18-24.

BackgroundChildhood arterial ischemic stroke is an important cause of morbidity and mortality in children. Hyperacute treatment strategies remain controversial and challenging, especially in the setting of increasingly proven medical and endovascular options in adults. Although national and international pediatric guidelines have given initial direction about acute therapy and management, pediatric centers have traditionally lacked the infrastructure to triage, diagnose, and treat childhood arterial ischemic stroke quickly.MethodsIn the past 10 years, researchers in the International Pediatric Stroke Study and Thrombolysis in Pediatric Stroke study have initiated early strategies for establishing pediatric specific stroke alerts.ResultsWe review the rationale, process and components necessary for establishing a pediatric stroke alert.ConclusionDevelopment of pediatric stroke protocols and pathways, with evidence-based acute management strategies and supportive care where possible, facilitates the evaluation, management, and treatment of an acute pediatric stroke.Copyright © 2016 Elsevier Inc. All rights reserved.

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