• The Journal of pediatrics · Dec 2002

    Inhaled prostacyclin for term infants with persistent pulmonary hypertension refractory to inhaled nitric oxide.

    • Lisa K Kelly, Nicolas F m Porta, Denise M Goodman, Christopher L Carroll, and Robin H Steinhorn.
    • Department of Pediatrics, Children's Memorial Hospital and Northwestern University Medical School, Chicago, Illinois 60614, USA.
    • J. Pediatr. 2002 Dec 1; 141 (6): 830-2.

    AbstractWe report the use of inhaled prostacyclin (PGI(2)) in 4 neonates with persistent pulmonary hypertension and hypoxemia refractory to inhaled nitric oxide. Oxygenation rapidly improved after inhalation of PGI(2) in all infants. The condition of one infant subsequently deteriorated, and alveolar capillary dysplasia was found at autopsy. The surviving infants were discharged with normal oxygen saturations in room air.

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