• J Invest Surg · Oct 2017

    Review Meta Analysis

    The Effectiveness of Bariatric Surgery for Chinese Obesity in 2 Years: A Meta-Analysis and Systematic Review.

    • Tianshu Zeng, Yuli Cai, and Lulu Chen.
    • a Department of Endocrinology , Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan , China.
    • J Invest Surg. 2017 Oct 1; 30 (5): 332-341.

    AimBariatric surgery is becoming an acceptable option for treatment of obesity worldwide, but there is no systemic review and meta-analysis focusing on obese patients in China. This study is to quantify the overall effects of bariatric surgery for Chinese obesity using up-to-date, comprehensive data.MethodsWe systematically searched MEDLINE, EMBASE, Cochrane Library, ISI Web of Science, and CNKI databases in English and Chinese. The weighted mean difference (MD) and 95% confidence interval (CI) were calculated from the original literature. Obese Chinese adults (body mass index [BMI] ≥ 30 kg/m2) with a minimum six-month follow-up were included.ResultsThe meta-analysis included 23 literature reviews with 1,316 morbidly Chinese obese adults. Bariatric surgery could significantly decrease the levels of BMI (MD = 10.75 kg/m2, 95% CI: 8.65-12.85, p <.01) and hemoglobin A1c (MD = 2.15%, 95% CI: 1.55-2.75, p <.00001), and improve lipid profile dramatically. In the subgroup analysis by BMI values, subjects lost more weight in BMI ≥ 40 kg/m2 group (MD = 14.01 kg/m2, 95% CI: 11.20-16.82) than BMI < 40 kg/m2 group (MD = 8.09 kg/m2, 95% CI: 6.49-9.68, p <.00001) after surgery. When we stratified analysis by surgical procedures, fasting blood glucose decreased more in gastric bypass group (MD = 3.08 mmol/L, 95% CI: 2.18-3.98) than restrictive procedures (MD = 1.27 mmol/L, 95% CI: 0.45-2.09, p =.008) and postprandial blood glucose levels (gastric bypass procedures: 8.44 mmol/L, 95% CI: 6.83-10.04; restrictive procedures: MD = 2.80 mmol/L, 95% CI: 1.86-3.74, p <.00001).ConclusionsBariatric surgery provides substantial metabolic effects for Chinese morbid obese adults at least in a relative short term. Further high-quality randomized controlled trials with long follow-up periods are needed to provide more reliable evidence.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…