Ischemia-modified albumin and cardiovascular risk markers in

Fertility and sterility · Jan 2011

Comparative Study

Ischemia-modified albumin and cardiovascular risk markers in polycystic ovary syndrome with or without insulin resistance.

The aim of this study was to evaluate ischemia-modified albumin levels (IMA) in polycystic ovary syndrome (PCOS) cases with and without insulin resistance and the correlation of IMA with carotid intima media thickness, homocysteine, and high-sensitivity C-reactive protein levels. Significantly higher levels of IMA in young lean PCOS cases, more relevant in insulin resistant cases, indicates chronic hypoxia and oxidative stress which might play a role in the metabolic consequences in PCOS.

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- Gamze S Caglar, Efser Oztas, Demet Karadag, Recai Pabuccu, and Selda Demirtas.
- Department of Obstetrics and Gynecology, Faculty of Medicine, University of Ufuk, Ankara, Turkey. gamzesinem@hotmail.com
- Fertil. Steril. 2011 Jan 1; 95 (1): 310-3.
AbstractThe aim of this study was to evaluate ischemia-modified albumin levels (IMA) in polycystic ovary syndrome (PCOS) cases with and without insulin resistance and the correlation of IMA with carotid intima media thickness, homocysteine, and high-sensitivity C-reactive protein levels. Significantly higher levels of IMA in young lean PCOS cases, more relevant in insulin resistant cases, indicates chronic hypoxia and oxidative stress which might play a role in the metabolic consequences in PCOS.Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

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Ischemia-modified albumin and cardiovascular risk markers in polycystic ovary syndrome with or without insulin resistance.

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