• La Revue du praticien · Sep 1994

    [Pain in humans: experimental facts and hypotheses].

    • P Cesaro.
    • Département de neurosciences médicales, Centre hospitalier universitaire Henri-Mondor, Créteil.
    • Rev Prat. 1994 Sep 15; 44 (14): 1875-9.

    AbstractThe description of painful phenomena in humans has to take into account its different components: sensory component (relevant to nociception), affective and emotional components. Nociceptor's (physiology is best understood with electrophysiological and neurochemical methods allowing a clear description of hyperalgesia, with its peripheral and spinal mechanisms. A functional model is partly available to explain allodynia, spontaneous burning pain and lightning pain, the three main consequences following deafferentation. At the thalamo-cortical level, one can describe nociceptive pathways and other pathways or neuronal networks involved in the affective and emotional components of pain.

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