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- Kurt Grelck, Noelle Stewart, Les Rosen, and Sean Sukal.
- Forefront Dermatology, Stevens Points, Wisconsin, USA.
- Cutis. 2015 Oct 1; 96 (4): E18-21.
AbstractAcute generalized exanthematous pustulosis (AGEP) is a potentially widespread, pustular, cutaneous eruption commonly associated with drug administration. We report a case of AGEP associated with the antianginal, anti-ischemic agent ranolazine. The patient, an 83-year-old man, had a validation score of 10 out of 12 in accordance with the EuroSCAR criteria (8-12 is considered definitive), although it may have been higher had blood work been performed prior to diagnosis and treatment. After ranolazine was discontinued and a course of tapered oral prednisone was prescribed, the rash resolved with subsequent desquamation.
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