• Samir S Keblawi, Jason N Wright, Jeffrey P Otjen, Arushi Verma, Emily C Brown, Kate D Ness, and Kenneth W Feldman.
• From the Multicare, Spokane.
• Pediatr Emerg Care. 2021 Jun 1; 37 (6): e339e341e339-e341.

BackgroundWhen evaluating an infant with unexplained fractures for child abuse, it is important to evaluate for possible causes of underlying bone fragility.CaseA 7-month-old infant was found to have a parathyroid hormone (PTH)-related peptide-secreting mesoblastic nephroma. In spite of having an elevated serum calcium, depressed serum phosphate, and high levels of PTH-related peptide, he had no demineralization or other hyper parathyroid-related bone changes. Instead, he had multiple classic metaphyseal lesions, fractures of differing ages including a proximal clavicle fracture, and current and past bruising. No fractures typical of bone insufficiency were present. These findings are highly indicative of abuse in addition to his hormone-secreting tumor.ConclusionsIn spite of this child's abuse findings, endogenous or tumor-related hyper PTH should be in the differential of underlying bone fragility. Children with disorders that could cause injury susceptibility can also be abused.Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.

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