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Critical care clinics · Jan 2019
ReviewComplications of Solid Organ Transplantation: Cardiovascular, Neurologic, Renal, and Gastrointestinal.
- Ayan Sen, Hannelisa Callisen, Stacy Libricz, and Bhavesh Patel.
- Department of Critical Care Medicine, Mayo Clinic Arizona, 5777 East Mayo Boulevard, Phoenix, AZ 85054, USA. Electronic address: Sen.Ayan@mayo.edu.
- Crit Care Clin. 2019 Jan 1; 35 (1): 169-186.
AbstractDespite improvements in overall graft function and patient survival rates after solid organ transplantation, complications can lead to significant morbidity and mortality. Cardiovascular complications include heart failure, arrhythmias leading to sudden death, hypertension, left ventricular hypertrophy, and allograft vasculopathy in heart transplantation. Neurologic complications include stroke, posterior reversible encephalopathy syndrome, infections, neuromuscular disease, seizure disorders, and neoplastic disease. Acute kidney injury occurs from immunosuppression with calcineurin inhibitors or as a result of graft failure after kidney transplantation. Gastrointestinal complications include infections, malignancy, mucosal ulceration, perforation, biliary tract disease, pancreatitis, and diverticular disease. Immunosuppression can predispose to infections and malignancy.Published by Elsevier Inc.
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