• Chethan M Puttarajappa, Jose F Bernardo, and John A Kellum.
• Renal-Electrolyte Division, University of Pittsburgh Medical Center, 3550 Terrace Street, Pittsburgh, PA 15261, USA. Electronic address: puttarajappacm@upmc.edu.
• Crit Care Clin. 2019 Jan 1; 35 (1): 61-73.

AbstractRenal complications are common following heart and/or lung transplantation and lead to increased morbidity and mortality. Renal dysfunction is also associated with increased mortality for patients on the transplant wait list. Dialysis dependence is a relative contraindication for heart or lung transplantation at most centers, and such patients are often listed for a simultaneous kidney transplant. Several factors contribute to the impaired renal function in patients undergoing heart and/or lung transplantation, including the interplay between cardiopulmonary and renal hemodynamics, complex perioperative issues, and exposure to nephrotoxic medications, mainly calcineurin inhibitors.Copyright © 2018 Elsevier Inc. All rights reserved.

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