• J Comput Assist Tomogr · Mar 2008

    Clinical Trial

    Acute chest pain with normal coronary angiogram: role of contrast-enhanced multidetector computed tomography in the differential diagnosis between myocarditis and myocardial infarction.

    • Loic Boussel, Delphine Gamondes, Patrick Staat, Brett M Elicker, Didier Revel, and Philippe Douek.
    • Department of Radiology, University of California, San Francisco, CA, USA. loic.boussel@gmail.com
    • J Comput Assist Tomogr. 2008 Mar 1; 32 (2): 228-32.

    ObjectiveTo evaluate the accuracy of delayed-enhanced multidetector computed tomography (MSCT) for differentiating between myocarditis and myocardial infarction in patients with normal x-ray coronary angiography.MethodsTwelve consecutive patients referred for acute chest pain and normal coronary arteries on x-ray coronary angiography were involved in this study. Delayed-enhanced MSCT and postgadolinium delayed-enhanced magnetic resonance imaging (MRI) examinations were performed within 36 hours and 4 days, respectively, after patient admission. Comparison between delayed-enhanced MSCT and MRI was performed by 3 independent blinded observers in term of final diagnosis, number of involved segments, and transmural extent.ResultsFinal diagnosis between myocarditis and myocardial infarction was identical for delayed-enhanced MSCT and MRI with a significant agreement for number of involved segments and transmural extension. Interobserver reproducibility was good for both techniques.ConclusionsWe demonstrated that delayed-enhanced MSCT allows differentiation between myocardial infarction and myocarditis with the same accuracy at acute phase compared with MRI.

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