• J. Neurol. Neurosurg. Psychiatr. · Aug 2003

    Spatial vision in visually asymptomatic subjects at high risk for multiple sclerosis.

    • L Frisén.
    • Institute of Clinical Neuroscience, Sahlgren's Academy of Göteborg University, Sahlgren's Hospital, S-413 45 Göteborg, Sweden. lars.frisen@neuro.gu.se
    • J. Neurol. Neurosurg. Psychiatr. 2003 Aug 1; 74 (8): 1145-7.

    ObjectiveTo investigate the state of spatial vision in visually asymptomatic subjects at high risk for multiple sclerosis.MethodsFifteen subjects suffering a first neurological episode suggestive of multiple sclerosis in clinical presentation, immunological profile, and magnetic resonance imaging, were examined with a new, sensitive test of spatial vision, rarebit perimetry. None had symptoms or signs of optic neuropathy.ResultsResults of rarebit perimetry were significantly worse than those of 15 age matched normal controls (p=0.01); seven patients (47%) were outside normal limits. One patient only obtained abnormal results in high pass resolution perimetry.ConclusionsRarebit perimetry may help to close the sensitivity gap between clinical examinations and neuroimaging.

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