-
J. Neurol. Neurosurg. Psychiatr. · Sep 2003
Case ReportsHereditary diffuse leucoencephalopathy with spheroids.
- N Hancock, M Poon, B Taylor, and C McLean.
- Department of General Internal Medicine, Royal Hobart Hospital, Tasmania, Australia. nicole.hancock@dhhs.tas.gov.au
- J. Neurol. Neurosurg. Psychiatr. 2003 Sep 1; 74 (9): 1345-7.
AbstractHereditary diffuse leucoencephalopathy with spheroids (HDLS) is a rare inherited progressive leucoencephalopathy characterised by giant neuroaxonal swellings (spheroids) within the CNS white matter. The case is reported of a 45 year old woman with a rapidly progressive fulminant illness course characterised by progressive cognitive decline with depressive features. A presumed dominant inheritance pattern was elicited. This report reviews the literature on HDLS and the relation of this disorder to other conditions with giant neuroaxonal swellings.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..