• J Small Anim Pract · Jun 2015

    Case Reports

    Fentanyl-induced asystole in two dogs.

    • M Jang, W-G Son, and I Lee.
    • Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Seoul National University, Seoul, 151-742, South Korea.
    • J Small Anim Pract. 2015 Jun 1; 56 (6): 411-3.

    AbstractFentanyl is used in small animals for perioperative analgesia during anaesthesia. Severe bradycardia and asystole were observed on bolus administration of a 3 µg/kg loading dose of fentanyl in two dogs under isoflurane anaesthesia. Premedication with 10 µg/kg glycopyrrolate did not prevent asystole in the first case; and although bradycardia was treated with 5 µg/kg glycopyrrolate administered intravenously in the second case, the heart rate continuously decreased and asystole subsequently developed. Asystole in both cases was quickly corrected by intravenous administration of 0 · 04 mg/kg atropine and closed chest compressions. This case report describes asystole induced by fentanyl administration in isoflurane anaesthetised dogs. Atropine was more effective than glycopyrrolate in the treatment of fentanyl-induced asystole. © 2015 British Small Animal Veterinary Association.

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