• S López Cuenca, L Oteiza López, N Lázaro Martín, M M Irazabal Jaimes, M Ibarz Villamayor, A Artigas, and J A Lorente Balanza.
• Servicio de Medicina Intensiva y Grandes Quemados, Hospital Universitario de Getafe, Madrid, España.
• Med Intensiva. 2019 Oct 1; 43 (7): 395-401.

ObjectiveTo estimate the prevalence of frailty in patients admitted to the Intensive Care Unit (ICU) and its impact upon ICU mortality at 1 and 6 months.DesignA prospective observational cohort study was carried out.SettingSpanish ICU.InterventionNone.Patients And MethodsPatients≥65 years of age admitted to the ICU for>24hours. Variables were registered upon admission, and functional status was assessed by telephone calls 1 and 6 months after discharge from the ICU.Main Study VariablesAge, gender, frailty (FRAIL scale), functional status (Barthel, Lawton, Clinical Dementia Rating and NUTRIC score), days of mechanical ventilation (MV), functional score (APACHE II and SOFA), ICU mortality, and mortality 1 and 6 months after ICU discharge.ResultsA total of 132 patients were evaluated, of which 46 were frail (34.9%). Age of the frail versus non-frail patients: 78.8±7.2 and 78.6±6.4 years, respectively (P=.43); male gender: 43.8% versus 56.3% (P=.10); SOFA score: 4.7±2.9 versus 4.6±2.9 (P=.75); MV: 33.3% versus 66.7% (P=.75); days of MV: 5.6±15 versus 4.3±8.1 (P=.57); ICU mortality 13% versus 6% (P = .14), mortality at 1 month 24% versus 8% (P = .01), mortality 6 months 32% versus 15% (P = .03). Frailty is associated with mortality at one month (OR = 3.5, P <.05, 95% CI (1.22-10.03) and at 6 months after discharge from the ICU (OR = 2.62, P <.05, 95% CI (1.04-6.56).ConclusionsFrailty was present in 35% of the patients admitted to the ICU, and was associated with mortality.Copyright © 2019 The Author(s). Publicado por Elsevier España, S.L.U. All rights reserved.

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