• BMJ case reports · Sep 2014

    Case Reports

    Nabilone therapy for cannabis withdrawal presenting as protracted nausea and vomiting.

    • Philip W Lam and David W Frost.
    • Division of General Internal Medicine, University Health Network, Toronto, Canada.
    • BMJ Case Rep. 2014 Sep 22; 2014.

    AbstractCannabis is one of the most commonly used recreational drugs worldwide. Psychoactive properties of the principal compound, δ-9-tetrahydrocannabinol include euphoria, a sense of relaxation and increased appetite. Chronic cannabis use has been associated with the development of a withdrawal syndrome on abrupt discontinuation. Withdrawal symptoms typically begin within 24 h of abstinence and manifest as irritability, nervousness, sleep disturbances and decreased appetite. There is growing evidence that supports the use of plant-derived and synthetic cannabinoids for the treatment of cannabis withdrawal. In this case report, we present 20-year-old woman who developed protracted nausea and vomiting secondary to cannabis withdrawal and was successfully treated with nabilone. Nausea and vomiting is not listed in the Diagnostic and Statistical Manual-5 diagnostic criteria for cannabis withdrawal syndrome and is an uncommon symptom presentation.2014 BMJ Publishing Group Ltd.

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