• Pain Med · Dec 2000

    Case report: limbic system activation by intravenous lidocaine in a patient with a complex regional pain syndrome and major depression.

    • M S Leong and H B Solvason.
    • Department of Anesthesiology, Pain Management Services, Stanford University, School of Medicine, CA 94305-5117, USA. msleong@stanford.edu
    • Pain Med. 2000 Dec 1; 1 (4): 358-61.

    AbstractIntravenous lidocaine is used to treat various neuropathic pain states. Systemic local anesthetics have been reported to cause behavioral alteration via limbic system activation. This case report describes a dramatic behavioral change in a patient receiving intravenous lidocaine and suggests a possible use of lidocaine to discriminate somatic and affective pain characteristics.

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