• J. Cardiothorac. Vasc. Anesth. · Oct 2019

    Editorial Comment

    Bileaflet Prosthesis Design and Orientation Affect Fluid Shear, Residence Time, and Thrombus Formation.

    • Vi Vu and Karen May-Newman.
    • Bioengineering Program, Dept. of Mechanical Engineering, San Diego State University, San Diego, CA.
    • J. Cardiothorac. Vasc. Anesth. 2019 Oct 1; 33 (10): 2870-2872.

    AbstractThe orientation and design of bileaflet valve prosthesis in the mitral position affects the intraventricular blood flow and exposure to shear. The combination of the anatomic orientation and a small gap size of the St. Jude Medical valve produces an increase in shear exposure and blood residence time, which both predispose the formation of thrombus in the high shear gaps of the valve hinges.Copyright © 2019 Elsevier Inc. All rights reserved.

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