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- George I Jallo, Chanland Roonprapunt, Karl Kothbauer, Diana Freed, Jeff Allen, and Fred Epstein.
- Division of Pediatric Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. gjallo1@jhmi.edu
- Neurosurgery. 2005 Jul 1; 57 (1): E195; discussion E195.
Objective And ImportanceIntraspinal solitary fibrous tumors, which are rare mesenchymal tumors, have previously been reported as case reports. We review our experience and, to our knowledge, the first small institutional series with respect to clinical presentation, diagnosis, surgical management, pathohistological analysis, progression-free survival, and long-term outcome.Clinical PresentationIn this retrospective review, four patients (three male and one female) ranging in age from 17 to 59 years (mean, 38.5 yr) had spinal solitary fibromas located throughout the spinal canal. Three tumors were located in the thoracic region and one in the cervical spine. All patients presented with pain and paresthesia. Two patients had an associated spinal deformity. All had gross total resection as confirmed by postoperative imaging studies.InterventionAll four patients underwent surgical treatment for spinal solitary fibromas. None of these patients underwent irradiation or chemotherapy after surgery at our center; therefore, outcome was attributed to surgery alone. There were no surgical deaths, and the 5-year actuarial survival rate was 100%. At the most recent follow-up examination, neurological function was stable or improved in 90% of patients.ConclusionPatients with solitary fibrous tumors have a long survival. These tumors have an indolent course, and radiotherapy or chemotherapy seems to be unnecessary.
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