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- Melania Capasso.
- Centre for Cancer and Inflammation, Barts Cancer Institute, Queen Mary University of London, London, UK.
- Immunology. 2014 Oct 1; 143 (2): 131-7.
AbstractThe identification of the HVCN1 gene, encoding the only mammalian voltage-gated proton channel, prompted a number of studies on how proton channels affect cellular functions. As their expression is mainly restricted to immune cells, it is not surprising that proton channels regulate different aspects of immune responses. In this review, I will examine the current knowledge of voltage-gated proton channels in both innate and adaptive responses and assess the remaining outstanding questions.© 2014 John Wiley & Sons Ltd.
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