• Clinical nuclear medicine · Oct 2014

    Case Reports

    Serial FDG PET/CT in autoimmune encephalitis with faciobrachial dystonic seizures.

    • Albrecht Kunze, Robert Drescher, Katharina Kaiser, Martin Freesmeyer, Otto W Witte, and Hubertus Axer.
    • From the *Hans Berger Department of Neurology, †Department of Nuclear Medicine, and ‡Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany.
    • Clin Nucl Med. 2014 Oct 1; 39 (10): e436-8.

    AbstractAutoimmune encephalitis (AE) is increasingly recognized as a nonparaneoplastic disorder with autoantibodies to neuronal proteins. Although MRI is frequently unremarkable, PET imaging might contribute to identification of affected brain regions in distinct AE. We report on serial FDG PET in a 72-year-old man with particular AE subtype, with potassium channel complex antibodies and prodromal stage with dystonic seizures. Serial FDG PET/CT revealed that besides limbic structures, basal ganglia are centrally involved and presumably play a key role in the generation of dystonic seizures.

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