• Andrei Ionut Cucu, Claudia Florida Costea, Antonio Perciaccante, Alexandru Carauleanu, Serban Turliuc, Bogdan Costachescu, Ion Poeata, and Mihaela Dana Turliuc.
• Neurosurgery Clinic, "Prof. Dr. N. Oblu" Emergency Clinical Hospital, Iasi, Romania.
• World Neurosurg. 2019 Aug 1; 128: 37-46.

BackgroundIntracranial meningiomas are brain tumors that have probably been known the longest, largely because of the occasional production of grotesque cranial deformities that have attracted the attention and interest of humankind. Because of the tendency of some intracranial meningiomas to cause skull deformation and thickening, these tumors have given rise to various speculations and theories related to their origin, starting in prehistoric times up to the present.MethodsFrom the Steinheim skull and "pharaonic meningiomas" to the first meningioma monograph and the first explanations of Harvey Cushing regarding the mechanism of hyperostosis, this review aims to weave again the story of Arachne. We identify the main contributors who have tried to understand and explain the tendency of some of these tumors to cause hyperostosis or other skull bone involvements.ConclusionsThe contribution of neurosurgeons or pathologists over the centuries is of undeniable importance and is the basis for understanding future molecular mechanisms.Copyright © 2019 Elsevier Inc. All rights reserved.

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