• Kento Takebayashi, Kotaro Kohara, Isamu Miura, Masahito Yuzurihara, Motoo Kubota, and Takakazu Kawamata.
• Department of Spinal Surgery, Kameda Medical Center, Chiba, Japan; Department of Neurosurgery, Tokyo Women's Medical University, Tokyo, Japan. Electronic address: tikurin0221@yahoo.co.jp.
• World Neurosurg. 2019 Aug 1; 128: 289-294.

BackgroundGanglioneuroma is a well-differentiated benign tumor that develops from the ganglion cells of the posterior mediastinum, retroperitoneum, cervical spine, and adrenal glands. The paravertebral body, in which the sympathetic trunk exists, is a common tumor site, and tumor sometimes invades the spinal canal through the intervertebral foramen. There have been no reports regarding tumors with intradural and extradural continuity. We report a paravertebral ganglioneuroma extending between the intradural and extradural spaces and its surgical treatment.Case DescriptionA 33-year-old man was admitted to the hospital with progressive left lower limb numbness. A dumbbell-type tumor progressing to the spinal canal via the left intervertebral foramen from the paravertebral body at L1-2 was detected, and intradural calcified lesions were found. Pathologic examination of a computed tomography-guided biopsy sample revealed a ganglioglioma. The extradural tumor was removed; however, the left lower limb pain gradually worsened. As complete block was observed on myelography, the intradural tumor was removed 8 months later. Intraoperative findings revealed that the intradural and extradural tumors were continuous through the L1 nerve root.ConclusionsThis is the first known reported case of paravertebral ganglioneuroma presenting in continuity between the intradural and extradural spaces.Copyright © 2019 Elsevier Inc. All rights reserved.

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