• Eur Spine J · Feb 2001

    Comparative Study

    Biomechanical compression tests with a new implant for thoracolumbar vertebral body replacement.

    • C Knop, U Lange, L Bastian, M Oeser, and M Blauth.
    • Department of Trauma Surgery, Hannover Medical School, 30623 Hannover, Germany. Dr.Christian.Knop@T-Online.de
    • Eur Spine J. 2001 Feb 1; 10 (1): 30-7.

    AbstractThe authors present an investigation into the biomechanical functioning of a new titanium implant for vertebral body replacement (Synex). Possible indications are fractures and/or dislocations with damage of the anterior column, posttraumatic kyphosis and tumors of the thoracolumbar spine. The construction must be supplemented by a stabilizing posterior or anterior implant. For best fit and contact with adjacent end-plates, Synex is distractable in situ. We performed comparative compression tests with Synex and MOSS ("Harms mesh cage") on human cadaveric specimens of intact vertebrae (L1). The aim of the study was to measure the compressive strength of the vertebral body end-plate in uniaxial loading via both implants to exclude collapse of Synex in vivo. Twelve human cadaveric specimens of intact vertebrae (L1) were divided into two identical groups (matched pairs) according to bone mineral density (BMD), determined using dual-energy quantitative computed tomography (DE-QCT). The specimens were loaded with an axial compression force at a constant speed of 5 mm/min to failure, and the displacement was recorded with a continuous load-displacement curve. The mean ultimate compression force (Fmax) showed a tendency towards a higher reading for Synex: 3396 N versus 2719 N (non-significant). The displacement until Fmax was 2.9 mm in the Synex group, which was half as far as in the MOSS group (5.8 mm). The difference was significant (P < 0.001). The compression force was twice as high, and significantly (P < 0.05) higher with Synex at displacements of 1 mm, 1.5 mm and 2 mm. A significant (P < 0.001) correlation (R = 0.89) between Fmax and BMD was found. Synex was found to be at least comparable to MOSS concerning the compressive performance at the vertebral end-plate. A possible consequence of the significantly higher mean compression forces between 1 and 2 mm displacement might be decreased collapse of the implant into the vertebral body in vivo.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…