• Early human development · Jul 2010

    Review

    Risk factors and prevention of late-onset sepsis in premature infants.

    • L Corbin Downey, P Brian Smith, and Daniel K Benjamin.
    • Department of Pediatrics, Children's Hospital of The King's Daughters, Norfolk, VA, USA.
    • Early Hum. Dev. 2010 Jul 1; 86 Suppl 1: 7-12.

    AbstractLate-onset sepsis in premature infants is a major cause of morbidity, mortality, and increased medical costs. Risk factors include low birth weight, low gestational age, previous antimicrobial exposure, poor hand hygiene, and central venous catheters. Methods studied to prevent late-onset sepsis include early feedings, immune globulin administration, prophylactic antimicrobial administration, and improved hand hygiene. In this review, we will outline the risk factors for development of late-onset sepsis and evidence supporting methods for prevention of late-onset sepsis in premature infants.Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.

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