• Paediatric anaesthesia · Apr 2013

    Case Reports

    Propofol infusion syndrome or adrenoleukodystrophy?

    • Yucel Karaman, Aylin Goktay, Hasan Agin, and Utku Karaarslan.
    • Anesthesiology and Reanimation Clinic, Tepecik Research and Training Hospital, Izmir, Turkey. dr_ykaraman@hotmail.com
    • Paediatr Anaesth. 2013 Apr 1;23(4):368-70.

    AbstractFollowing a propofol anesthetic, a 5-year-old girl with lower extremity spasticity seized and developed hypertriglyceridemia, hyperkalemia, and metabolic acidosis. A presumed diagnosis of propofol infusion syndrome (PRIS) was made, but further investigation revealed neonatal adrenoleukodystrophy. PRIS should be considered with this constellation of symptoms, but other neurometabolic disorders must always be ruled out.© 2013 Blackwell Publishing Ltd.

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