• Liping Liu, Xinrui Liu, Limei Qu, Yi Zhang, and Yunqian Li.
• Department of Neurosurgery, The First Hospital of Jilin University, Changchun, Jilin Province, China.
• World Neurosurg. 2019 Sep 1; 129: 254-260.

BackgroundThis paper reports the case of a giant saddle area lymphoid epithelial carcinoma as reference for clinical diagnosis and treatment. The clinical data of 1 patient who suffered from giant saddle area lymphoid epithelial carcinoma that invaded the bilateral cavernous sinus and surrounding internal carotid artery, slope, nasopharynx, oropharynx, sphenoid sinus, and ethmoid sinus were retrospectively analyzed. The treatment process and relevant literature were summarized.Case DescriptionThe 68-year-old man was admitted to the hospital because of headache and dizziness for one half a year and aggravation of visual deterioration for 2 months. Magnetic resonance imaging showed a large mass in the saddle area, about 8.11 × 8.12 × 6.2 cm in size. Successful removal of the saddle mass was achieved under transnasal endoscopic approach, and postoperative pathology indicated lymphoid epithelial carcinoma. Visual acuity improved, and the patient recovered well after the operation.ConclusionsGiant saddle area lymphoid epithelial carcinoma is rare. Surgical removal should be selected as the initial treatment, and postoperative radiotherapy is indispensable for lymphoid epithelial carcinoma of the skull base and sinus.Copyright © 2019 Elsevier Inc. All rights reserved.

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