• World Neurosurg · Sep 2019

    Case Reports

    Infantile optic pathway glioblastoma: a case report.

    • Declan G Siedler, Jessica C Beechey, Peter J Jessup, and Nova B Thani.
    • Department of Neurosurgery, Royal Hobart Hospital, Hobart, Tasmania, Australia.
    • World Neurosurg. 2019 Sep 1; 129: 172-175.

    BackgroundOptic pathway gliomas and glioblastomas remain a rare entity within the infant population.Case DescriptionWe outline the case of a 6-month-old female who presented with failure to thrive, nystagmus and features of raised intracranial pressure. Subsequent magnetic resonance imaging demonstrated an infiltrating tumor radiating from the optic nerves bilaterally. She underwent emergent ventriculoperitoneal shunting and biopsy. Histology confirmed a World Health Organization grade IV glioblastoma.ConclusionsThe patient remained clinically and radiologically stable at 1 year. Optic pathway glioblastoma in this population is a previously undescribed entity that requires multidisciplinary input to guide ongoing therapy.Copyright © 2019 Elsevier Inc. All rights reserved.

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