• Clinical rehabilitation · Mar 2010

    Randomized Controlled Trial Multicenter Study

    Evaluation of an adjustment group for people with multiple sclerosis: a pilot randomized controlled trial.

    • A C Forman and N B Lincoln.
    • Institute of Work, Health and Organisations, University of Nottingham, Nottingham, UK. nadina.lincoln@nottingham.ac.uk
    • Clin Rehabil. 2010 Mar 1; 24 (3): 211-21.

    ObjectiveThe aim was to evaluate a group treatment for people with multiple sclerosis and low mood.DesignRandomized controlled trial.SettingCommunity.ParticipantsPatients with multiple sclerosis and low mood, scoring >7 on the Hospital Anxiety and Depression Scales or >2 on the General Health Questionnaire 12.InterventionsParticipants either attended an adjustment group for six, 2-hour group treatment sessions or were on a waiting list to attend the group.OutcomesHospital Anxiety and Depression Scale, General Health Questionnaire 12, Multiple Sclerosis Self Efficacy Scale, Multiple Sclerosis Impact Scale and Short Form 36 administered 3 and 6 months after random allocation.ResultsOf the 219 patients identified, 100 (46%) reported depressive symptoms and 126 (58%) anxiety symptoms. Forty participants were recruited, aged 25-68 (mean 47.7 SD 9.7) and eight were men. Patients allocated to the group intervention reported fewer depressive symptoms than those in the control group (U 109.5, P<0.05) but there were no significant differences in anxiety symptoms, self-efficacy or quality of life.ConclusionDepressive symptoms were reduced following group intervention, which suggests this may be an effective psychological treatment and warrants further evaluation.

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