• Mohammadreza Maleki Verki, Samaneh Porozan, Hassan Motamed, Mohammad Ali Fahimi, and Adel Aryan.
• Emergency Medicine Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
• Am J Emerg Med. 2019 Jun 1; 37 (6): 1033-1036.

BackgroundUreter muscles contraction movements caused pain in renal colic. Magnesium sulphate could influence the pain by reducing acetylcholine in the nerve terminals. We have aimed to evaluate the analgesic effects of magnesium sulphate on acute renal colic pain.MethodIn this double-blind clinical trial study, the patients with renal colic pain were randomly divided into 2 groups; Group I received an intravenous infusion of 30 mg of Ketorolac and normal saline as placebo, Group II 50 mg/kg magnesium sulphate 50%/100 ml normal plus 30 mg of Ketorolac. The pain severity of patients was assessed using the visual analog scale (VAS) at baseline, and 15 and 30 min after intervention.ResultsBaseline pain score and demographic characteristics did not significantly different between the groups. After 30 min the pain score significantly reduced in both groups. While, at 15 and 30 min, mean pain score did not show statistically significant differences.ConclusionOur findings indicated that Magnesium sulphate did not influence renal colic pain relief.Copyright © 2018 Elsevier Inc. All rights reserved.

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