• Scott S Oh, W Dean Wallace, Faisal Shaikh, and Joseph P Lynch.
• Division of Pulmonary, Critical Care Medicine, Clinical Immunology, and Allergy, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California.
• Semin Respir Crit Care Med. 2018 Dec 1; 39 (6): 637-648.

AbstractTransbronchial lung cryobiopsy (TBLCB) is a relatively new and promising technique for the acquisition of larger amounts of higher quality lung tissue for the diagnosis of lung diseases. There is a growing body of literature describing a diagnostic yield comparable to surgical lung biopsy with a favorable safety profile. Due to its advantages TBLCB has garnered significant interest with more institutions beginning to adopt this technique. However, several questions remain including its role in the diagnostic algorithm, indications, and technique. Herein we provide a review of the available literature describing diagnostic yield, complications, and differing techniques as well as a perspective from pathology.Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

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