• Wolfgang Huber, Barbara Jeschke, Bernhard Kreymann, Michael Hennig, Michael Page, Hermann Salmhofer, Florian Eckel, Ulrike Schmidt, Andreas Umgelter, Ursula Schweigart, and Meinhard Classen.
• Department of Internal Medicine II, Klinikum Rechts der Isar, Technical University of Munich, Germany. Wolfgang.Huber@t-online.de
• Invest Radiol. 2002 Sep 1; 37 (9): 471-81.

Rationale And ObjectivesTo investigate whether haemodialysis prevents contrast-induced nephropathy (definition: increase of serum-creatinine of >or= 0.5 mg/dL within 7 days).Materials And MethodsThirty-one patients (mean serum-creatinine 4.01 +/- 1.83 mg/dL) were dialyzed for 4.36 +/- 1.0 hours within one hour after 278.4 +/- 160.5 mL of contrast medium.ResultsDialysis resulted in a significant reduction of serum-creatinine (2.25 +/- 1.46 mg/dL; P< 0.0001) and stable mean serum-creatinine levels 2, 3, 4, and 7 days after contrast medium and at discharge compared with baseline values. However, 19 patients (61%) developed contrast-induced nephropathy within 7 days. Four patients had to be repeatedly dialyzed. A comparison of our patients' 48 hours-incidence of contrast-induced nephropathy (9/31; 29%) versus patients at comparable risk included in seven previous studies demonstrated a prophylactic effect of dialysis only versus a subgroup in one study.ConclusionsData provide no hint that haemodialysis prevents contrast-induced nephropathy. Therefore, postprocedural dialysis should be restricted to patients participating in clinical studies.

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