• World Neurosurg · Sep 2019

    Case Reports

    Three-level lumbar en bloc spondylectomy with 3D-printed vertebrae reconstruction for recurrent giant cell tumor.

    • Brian Zhaojie Chin, Tao Ji, Xiaodong Tang, Rongli Yang, and Wei Guo.
    • Musculoskeletal Tumor Center, People's Hospital, Peking University, Beijing, China; University Orthopaedics, Hand and Reconstructive Microsurgical Cluster, National University Health System, Singapore.
    • World Neurosurg. 2019 Sep 1; 129: 531-537.e1.

    BackgroundPrimary malignancies involving the mobile spine often require total en bloc spondylectomy with complex mechanical reconstruction, which can be augmented with novel application of the 3-dimensional (3D)-printing technique.Case DescriptionA 51-year-old man presented with a 12-month history of progressive thigh pain and lower limb motor function loss, 36 months after T12-L4 instrumentation and fusion for giant cell tumor (GCT) of the L2 vertebrae before referral. The patient subsequently underwent successful curative management of recurrent GCT through denosumab treatment, L1-L3 total en bloc spondylectomy (TES), and a novel lumbopelvic reconstruction method with a 3D-printed lumbar vertebrae and screw-rod system.ConclusionsTo our knowledge, this is the first reported case of multilevel lumbar TES for GCT reconstructed using a 3D-printed vertebrae. Although TES-specifically in the lumbosacral spine-remains challenging due to its unique anatomy and increased risk of neurologic insult, it is an effective option for curative management of GCTs.Copyright © 2019 Elsevier Inc. All rights reserved.

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