• World Neurosurg · Sep 2019

    The effectiveness of lumbar drainage in the management of the delayed or recurrent cerebrospinal fluid leaks: a retrospective study of case series in a single center.

    • ShuangMin Fan, YaXin Chen, Yi Cao, LunXin Liu, FuJun Liu, ChangWei Zhang, and LiangXue Zhou.
    • Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, P.R. China.
    • World Neurosurg. 2019 Sep 1; 129: e845-e850.

    ObjectiveLittle is known about the effectiveness of lumbar drainage (LD) in the treatment of delayed or recurrent cerebrospinal fluid (CSF) leaks. We report our institutional experience and the effectiveness of LD in the management of delayed or recurrent CSF leaks.MethodsBetween January 2014 and December 2018, a total 21 patients with delayed or recurrent CSF leaks were enrolled in the research. All patients were treated conservatively for 48 hours, and LD was prescribed if CSF leaks still existed after 48 hours. If LD failed, endoscopic endonasal surgery (EES) was performed as soon as possible. Medical records were collected to analyze the effectiveness of LD.ResultsAmong 21 patients, 4 patients experienced resolution with conservative treatment, and 17 patients were treated by CSF diversion by LD. The total cure rate of LD was 9/17 (52.9%). The cure rate was not statistically significantly different (relative risk = 3.33; Fisher exact test P = 0.131) between the traumatic group (8/12, 66.7%) and the transsphenoidal surgery group (1/5, 20.0%). During the follow-up time, no recurrence of CSF leaks was observed.ConclusionsThe cure rate of LD in delayed or recurrent CSF leaks was lower than that of initial treatment with LD. The cure rate in the traumatic group tended to be higher than that in the transsphenoidal surgery group. EES can be used as a remedial treatment for patients in whom LD has failed.Copyright © 2019 Elsevier Inc. All rights reserved.

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