• Anesthesia and analgesia · Jul 2019

    Survival of Staphylococcus epidermidis in Propofol and Intralipid in the Dead Space of Intravenous Injection Ports.

    • Ronan M N Noble, Saad Y Salim, Bradley Walker, Rachel G Khadaroo, Angelo B Chiarella, Ferrante S Gragasin, and Stephane L Bourque.
    • From the Departments of Anesthesiology & Pain Medicine.
    • Anesth. Analg. 2019 Jul 1; 129 (1): e20-e22.

    AbstractWe tested whether propofol or Intralipid inoculated with Staphylococcus epidermidis would promote bacterial growth within an intravenous (IV) injection hub, a site prone to bacterial contamination. In tubes incubated under optimal conditions, S epidermidis exhibited growth in Intralipid, but not in propofol. In contrast, within the IV hub incubated with either propofol or intralipid at room temperature, S epidermidis bacterial numbers declined with time, and virtually no contamination remained after 12 hours. These data suggest that certain IV lines are inhospitable for S epidermidis.

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