• Anesthesia and analgesia · Jul 2019

    Randomized Controlled Trial Comparative Study

    Personalized Versus Protocolized Fluid Management Using Noninvasive Hemodynamic Monitoring (Clearsight System) in Patients Undergoing Moderate-Risk Abdominal Surgery.

    • Alexandre Joosten, Shalini Raj Lawrence, Alexandra Colesnicenco, Sean Coeckelenbergh, Jean Louis Vincent, Philippe Van der Linden, Maxime Cannesson, and Joseph Rinehart.
    • From the Department of Anesthesiology, Cliniques Universitaires de Bruxelles (CUB) Erasme, Université Libre de Bruxelles, Brussels, Belgium.
    • Anesth. Analg. 2019 Jul 1; 129 (1): e8-e12.

    AbstractAdvances in noninvasive hemodynamic monitoring systems allow delivery of goal-directed fluid therapy and could therefore be used in less-invasive surgical procedures. In this randomized controlled trial, we compared closed-loop-assisted goal-directed fluid therapy using a noninvasive cardiac output (Clearsight system) monitor (personalized approach) to a protocolized fluid therapy approach in 40 patients undergoing moderate-risk laparoscopic abdominal surgery. Cardiac output and stroke volume variations were not significantly different in both groups and remained within predefined target values >90% of the study time. Personalized fluid therapy does not seem to offer any hemodynamic advantage over a protocolized approach in this population.

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