• Diewertje Sluik, Anouk Geelen, Jeanne H M de Vries, Simone J P M Eussen, Henny A M Brants, Saskia Meijboom, Martien C J M van Dongen, H Bas Bueno-de-Mesquita, Wijckmans-Duysens Nicole E G NE 2Department of Epidemiology,Care and Public Health Research Institute/Cardiovascular Research Institute (CAPHRI/CARIM),Maastricht Universi, Pieter van 't Veer, Pieter C Dagnelie, Marga C Ocké, and Edith J M Feskens.
• 1Division of Human Nutrition,Wageningen University,PO Box 17, 6700 AA Wageningen,The Netherlands.
• Br. J. Nutr. 2016 Sep 1; 116 (5): 913-23.

AbstractA standardised, national, 160-item FFQ, the FFQ-NL 1.0, was recently developed for Dutch epidemiological studies. The objective was to validate the FFQ-NL 1.0 against multiple 24-h recalls (24hR) and recovery and concentration biomarkers. The FFQ-NL 1.0 was filled out by 383 participants (25-69 years) from the Nutrition Questionnaires plus study. For each participant, one to two urinary and blood samples and one to five (mean 2·7) telephone-based 24hR were available. Group-level bias, correlation coefficients, attenuation factors, de-attenuated correlation coefficients and ranking agreement were assessed. Compared with the 24hR, the FFQ-NL 1.0 estimated the intake of energy and macronutrients well. However, it underestimated intakes of SFA and trans-fatty acids and alcohol and overestimated intakes of most vitamins by >5 %. The median correlation coefficient was 0·39 for energy and macronutrients, 0·30 for micronutrients and 0·30 for food groups. The FFQ underestimated protein intake by an average of 16 % and K by 5 %, relative to their urinary recovery biomarkers. Attenuation factors were 0·44 and 0·46 for protein and K, respectively. Correlation coefficients were 0·43-0·47 between (fatty) fish intake and plasma EPA and DHA and 0·24-0·43 between fruit and vegetable intakes and plasma carotenoids. In conclusion, the overall validity of the newly developed FFQ-NL 1.0 was acceptable to good. The FFQ-NL 1.0 is well suited for future use within Dutch cohort studies among adults.

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