• Neurosurgery · Feb 2018

    Practice Guideline

    Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on Pathological Methods and Prognostic Factors in Vestibular Schwannomas.

    • Michael E Sughrue, Kar-Ming Fung, Jamie J Van Gompel, Jo Elle G Peterson, and Jeffrey J Olson.
    • Department of Neurosurgery, University of Oklahoma, Oklahoma City, Oklahoma.
    • Neurosurgery. 2018 Feb 1; 82 (2): E47-E48.

    Target PopulationAdults diagnosed with vestibular schwannomas.Question 1What is the prognostic significance of Antoni A vs B histologic patterns in vestibular schwannomas?RecommendationNo recommendations can be made due to a lack of adequate data.Question 2What is the prognostic significance of mitotic figures seen in vestibular schwannoma specimens?RecommendationNo recommendations can be made due to a lack of adequate data.Question 3Are there other light microscopic features that predict clinical behavior of vestibular schwannomas?RecommendationNo recommendations can be made due to a lack of adequate data.Question 4Does the KI-67 labeling index predict clinical behavior of vestibular schwannomas?RecommendationNo recommendations can be made due to a lack of adequate data.Question 5Does the proliferating cell nuclear antigen labeling index predict clinical behavior of vestibular schwannomas?RecommendationNo recommendations can be made due to a lack of adequate data.Question 6Does degree of vascular endothelial growth factor expression predict clinical behavior of vestibular schwannomas?RecommendationNo recommendations can be made due to a lack of adequate data.  The full guideline can be found at: https://www.cns.org/guidelines/guidelines-management-patients-vestibular-schwannoma/chapter_6.Copyright © 2017 by the Congress of Neurological Surgeons

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