• Medicina · Jan 2011

    Multicenter Study

    [Congenital junctional ectopic tachycardia. Pharmacologic management during infancy].

    • Mónica N Benjamín, Juan Infante, Julián Olmedo, Mauricio Abello, and José M Moltedo.
    • Servicio de Cardiología Pediátrica, Hospital de Niños de Córdoba, Buenos Aires, Argentina. monibenjamin@hotmail.com
    • Medicina (B Aires). 2011 Jan 1; 71 (6): 521-4.

    AbstractCongenital junctional ectopic tachycardia (JET) is a rare arrhythmia that can be refractory to medical therapy with high morbidity and mortality rates. The aim of this study was to report our experience with pharmacologic management of congenital JET in infants. Seven patients with congenital JET were identified between 2008 and 2010. Only two of them presented dilated cardiomyopathy. There were no congenital structural defects. Amiodarone was given to all the patients, as single therapy in one, and in combination with propranolol in four. In one patient flecainide was administered together with amiodarone and propranolol, and in another patient was used combined with amiodarone. During follow- up with an average time of 12.2 months (median 9.75 months, range 1-28 months), sinus rhythm alternating with slow junctional tachycardia was successfully achieved in 3 patients; no side effects were detected. There was only one death in our study group. The combination of different antiarrhythmics (amiodarone plus propranolol, and eventually flecainide) is a valid option for rhythm control and management of JET in infants.

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