• Tommaso Mauri, Eleonora Carlesso, Elena Spinelli, Cecilia Turrini, Corte Francesca Dalla FD Department of Morphology, Surgery and Experimental Medicine, Section of Anesthesia and Intensive Care, University of Ferrara, Italy., Riccarda Russo, Jean-Damien Ricard, Antonio Pesenti, Oriol Roca, and Giacomo Grasselli.
• Department of Pathophysiology and Transplantation, University of Milan, Italy; Department of Anesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. Electronic address: tommaso.mauri@unimi.it.
• J Crit Care. 2019 Oct 1; 53: 183-185.

AbstractThe ROX (Respiratory rate-OXygenation) index is an early predictor of failure of nasal high flow (NHF), with lower values indicating higher risk of intubation. We measured the ROX index at set flow rate of 30 and 60 l/min in 57 hypoxemic patients on NHF. Patients with increased ROX index values at higher flow (n = 40) showed worse baseline oxygenation, higher respiratory rate and lower ROX index in comparison to patients with unchanged or decreased ROX index values (n = 17). The ROX index variation between flows was correlated with the change in end expiratory lung volume. Set flow rate during NHF might impact the ROX index value.Copyright © 2019 Elsevier Inc. All rights reserved.

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