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Anesthesia and analgesia · May 2004
Case ReportsGeneral anesthesia for cesarean delivery in a patient with paroxysmal nocturnal hemoglobinuria and thrombocytopenia.
- Klaus Kjaer, Michele Comerford, and Farida Gadalla.
- Department of Anesthesiology, Weill Medical College of Cornell University, New York, New York 10021, USA. kkjaer@hotmail.com
- Anesth. Analg. 2004 May 1; 98 (5): 1471-2, table of contents.
UnlabelledPregnancy in patients with paroxysmal nocturnal hemoglobinuria (PNH) increases the risk of complement activation, hemolysis, and thrombosis. We describe the anesthetic management of a patient with PNH who underwent general anesthesia for cesarean delivery. Steroids, heparin, and blood products were administered early to minimize the likelihood of a hematologic emergency.ImplicationsPregnancy in patients with paroxysmal nocturnal hemoglobinuria increases the risk of hemolysis, thrombosis, anemia, and thrombocytopenia. We describe the anesthetic management of a patient with paroxysmal nocturnal hemoglobinuria and thrombocytopenia who underwent general anesthesia for cesarean delivery.
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