• Emerg. Med. Clin. North Am. · Aug 2019

    Review

    Intracranial Hemorrhage and Intracranial Hypertension.

    • Evie Marcolini, Christoph Stretz, and Kyle M DeWitt.
    • Department of Surgery, Division of Emergency Medicine, University of Vermont College of Medicine, 111 Colchester Avenue, Burlington, VT 05401, USA; Department of Neurology, Division of Neurocritical Care, University of Vermont College of Medicine, 111 Colchester Avenue, Burlington, VT 05401, USA. Electronic address: emarcolini@gmail.com.
    • Emerg. Med. Clin. North Am. 2019 Aug 1; 37 (3): 529-544.

    AbstractCentral nervous system hemorrhage has multiple pathophysiologic etiologies, including intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH), and traumatic brain injury (TBI). Given the nuances intrinsic to each of these etiologies and pathophysiologic processes, optimal blood pressure varies significantly and depends on type of hemorrhage and individual characteristics. This article reviews the most current evidence regarding blood pressure targets and provides guidance on reversal of anticoagulation for TBI, ICH, and SAH. It also describes the assessment, optimal therapeutic targets, and interventions to treat intracranial hypertension that can result from TBI, ICH, or SAH.Copyright © 2019 Elsevier Inc. All rights reserved.

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