• Elina Kyösti, Tero I Ala-Kokko, Pasi Ohtonen, Outi Peltoniemi, Hanna Ebeling, Michael Spalding, Paula Rautiainen, Janne Kataja, and Janne H Liisanantti.
• Medical Research Centre of Oulu University and Oulu University Hospital, Oulu, Finland.
• Pediatr Crit Care Me. 2019 Nov 1; 20 (11): e496-e502.

ObjectivesWe investigated the long-term psychologic symptoms of patients who survived pediatric intensive care admission.DesignLongitudinal follow-up study.SettingNationwide cohort study based on a national ICU register and a questionnaire survey.PatientsAll pediatric patients (0-16 yr old) who were admitted to an ICU in Finland in 2009-2010.InterventionsNone.Measurements And Main ResultsSix years after ICU admission, all surviving patients were sent the Strengths and Difficulties Questionnaire, and questionnaires regarding chronic diseases and need for medication and therapy. At the end of the follow-up period, there were 3,674 surviving children who had been admitted to an ICU in 2009-2010. Of these children, 1,105 completed the Strengths and Difficulties Questionnaire 6 years after admission. Strengths and Difficulties Questionnaire scores were abnormal for 84 children (7.6%), borderline for 80 (7.2%), and normal for 941 (85.2%). Participants with abnormal scores were younger at admission to the ICU (3.06 vs 4.70 yr; p = 0.02), and more commonly had a chronic disease (79.5% vs 47.4%; p < 0.001), a need for continuous medication (49.4% vs 31.7%; p < 0.001), a need for therapy (58.5% vs 15.9%; p < 0.001), and a need for annual healthcare visits (91.4% vs 85.2%; p = 0.05). Abnormal Strengths and Difficulties Questionnaire scores were associated with higher rates of neurologic (32.1% vs 10.2%), gastrointestinal (7.1% vs 3.9%), psychiatric (3.6% vs 0.5%), and chromosomal disorders (9.5% vs 1.3%), as well as with long-term pain (1.2% vs 0.6%).ConclusionsParticipants with abnormal Strengths and Difficulties Questionnaire scores (poor psychologic outcome) at 6 years after childhood ICU admission more commonly suffered neurologic, chromosomal, or psychiatric diagnoses or long-term pain, and generally required higher levels of healthcare services, therapies, and medication.

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