• Sang Hui Chu, Eun Jung Kim, Seok Hee Jeong, and Geu Lee Park.
• Nursing Policy and Research Institute, Biobehavioral Research Center, College of Nursing, Yonsei University, Seoul, Republic of Korea. shchu@yuhs.ac.
• Bmc Public Health. 2015 Jan 17; 15: 10.

BackgroundThis study was conducted to investigate awareness of clinical trials (CTs) including perceptions of favorable feelings about, necessity for, and safety of CTs, the ultimate beneficiary of CTs and the factors associated with willingness to participate in CTs among the general population in South Korea.MethodsA cross sectional survey study was conducted in a randomly selected national sample of 1,515 Korean.ResultsPerception toward CTs was measured using a scale from 0 (strongly disagree) to 10 (strongly agree). Respondents readily understood the necessity for CTs (M = 7.27, SD = 2.15); had moderately favorable feelings (M = 5.32, SD = 2.31) toward CTs and felt that these CTs were moderately safe (M =  .71, SD = 1.90). Twenty-five percent of the respondents answered that they would be willing to participate in a CT in the future. Perception of the ultimate benefits of CTs, awareness, favorable feelings, safety, and necessity regarding CTs were identified as significant predictors of willingness to participate in CTs.ConclusionAn awareness of CTs and the perceptions toward CTs were associated with general public willingness to participate in a CT. Findings from this study can be used in planning outreach and recruitment strategies, and to understand the predictors of CT participation.

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