• Kidney international · Aug 2011

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    Biomarker explorations in acute kidney injury: the journey continues.

    • Ravindra L Mehta.
    • Division of Nephrology and Hypertension, Department of Medicine, University of California, San Diego, San Diego, California 92103, USA. rmehta@ucsd.edu
    • Kidney Int. 2011 Aug 1; 80 (4): 332-4.

    AbstractDetermining whether an elevation in serum creatinine represents structural damage or a reversible functional change is a dilemma that clinicians encounter frequently. The emergence of kidney-specific biomarkers offers an opportunity to improve our discriminatory ability. Singer et al. provide new information on the utility of neutrophil gelatinase-associated lipocalin (NGAL) to distinguish pre-renal from established acute kidney injury. Although these results are promising, several caveats need to be considered and applied for future confirmatory studies.

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