• A D Fox, L Hands, and J Collin.
• University of Oxford, Nuffield Department of Surgery, John Radcliffe Hospital, Headington, U.K.
• Eur J Vasc Endovasc Surg. 1999 Apr 1; 17 (4): 343-6.

ObjectivesTo review our total experience of thoracoscopic sympathetic trunk transection for the treatment of palmar hyperhidrosis and second and third thoracic sympathetic ganglionectomy for axillary hyperhidrosis.DesignLongitudinal cohort study following up consecutive patients for 0.3 to 5.5 years.SubjectsFifty-four consecutive patients undergoing thoracoscopic sympathectomy for hyperhidrosis.MethodsProspective evaluation of immediate technical success, complications, late recurrence of hyperhidrosis and patient acceptability.Results100% initial cure for palmar hyperhidrosis, 91% of sympathetic ganglionectomies for axillary hyperhidrosis were technically successful and initially curative. Compensatory sweating 44% patients, most severe after bilateral sympathetic ganglionectomy. Complications occurred in 14% patients, all resolving without further intervention. There were no cases of Horner's syndrome. 13% patients reported a return of some palmar sweating. 5.4% patients developed recurrent palmar hyperhidrosis at 6, 15 and 21 months postoperatively.ConclusionTransection of the sympathetic trunk between the first and second thoracic sympathetic ganglia initially cures 100% of patients treated primarily for palmar hyperhidrosis. Technically successful 2nd and 3rd thoracic sympathetic ganglionectomy initially cures 100% of patients with axillary hyperhidrosis. Compensatory sweating is common after bilateral sympathectomy. Recurrent palmar hyperhidrosis occurs in 5.4% of cases, but can be cured by a second thoracoscopic sympathectomy. Horner's syndrome is an avoidable complication of thoracoscopic sympathectomy.

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