• Acta Anaesthesiol Taiwan · Dec 2006

    Serial changes of pulse wave velocity and correlations with hemodynamic parameters during general anesthesia.

    • Ying-Tzu Chen, Chang-Yao Chiayg, Ming-Cheng Wang, Wei-Chuan Tsai, Hsien-Tsai Wu, and Chi-Chu Liu.
    • Division of Anesthesiology, Sin Lau Christian Hospital, Tainan, Taiwan, ROC.
    • Acta Anaesthesiol Taiwan. 2006 Dec 1; 44 (4): 193-8.

    BackgroundIncreased pulse wave velocity (PWV) is a marker of increased arterial stiffness and is correlated with cardiovascular mortality and mortality of all causes in the elderly and in patients with essential hypertension and type 2 diabetes. There is also a positive correlation between PWV and arterial blood pressure. The changes of PWV in response to general anesthesia and surgical stimulation remain unclear. The aim of this study was to continuously monitor the PWV, blood pressure and heart rate, and to assess their correlations during general anesthesia in women receiving gynecologic surgery.MethodsThe values of PWV were obtained from calculation of the finger-to-toe distance divided by the transit time using dual-channel photoplethysmography system. The values of PWV, systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate were recorded before anesthesia induction, 5 min before incision, at incision, in continuation for at least 30 min thereafter, and 5 min after discontinuation of sevoflurane. The correlations between PWV and SBP, DBP and heart rate during the general anesthesia were analyzed using Pearson's correlation test.ResultsThe serial records of PWV and hemodynamic parameters showed that PWV, SBP, DBP, and heart rate decreased after induction of anesthesia. SBP and DBP increased after surgical incision. There was a trend of progressively declining of PWV and DBP during the general anesthesia but SBP and heart rate remained stationary. All the values of PWV, SBP, DBP, and heart rate increased after discontinuation of anesthesia. There were significant correlations between PWV and SBP (r = 0.4558, P < 0.0001), between PWV and DBP (r = 0.2719, P < 0.0001), between PWV and pulse pressure (r = 0.2067, P < 0.0001), and between PWV and mean arterial pressure (r = 0.3969, P < 0.0001).ConclusionsWe could evaluate the serial changes of PWV in response to general anesthesia and surgical stimulation using a simple and noninvasive dual-channel photoplethysmography system. The value of PWV, an index of arterial stiffness, has significant correlation with arterial blood pressure.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…