• Pier Woudstra, Maik J Grundeken, Robin P Kraak, Mariëlla E C J Hassell, E Karin Arkenbout, Jan Baan, Marije M Vis, Karel T Koch, Jan G P Tijssen, Jan J Piek, Robbert J de Winter, José P S Henriques, and Joanna J Wykrzykowska.
• Heartcenter, Academic Medical Center-University of Amsterdam, Amsterdam, the Netherlands.
• Am. Heart J. 2014 Feb 1; 167 (2): 133-40.

BackgroundThe Absorb everolimus-eluting bioresorbable vascular scaffold (AbsorbBVS) is a completely resorbable device engineered to overcome the limitations of permanent metallic stents, providing temporary scaffolding and antiproliferative drug delivery for the treatment of obstructive coronary artery disease.MethodsThe objective of the AIDA trial is to evaluate the efficacy and performance in an contemporary all-comer population of the AbsorbBVS strategy vs the XIENCE family everolimus-eluting metallic coronary stent system in the treatment of coronary lesions. The AIDA trial is a prospective, randomized (1:1), active-control, single-blinded, all-comer, noninferiority trial. A total of 2,690 subjects will be enrolled with broad inclusion and limited exclusion criteria according to the "Instructions for Use" of the AbsorbBVS strategy. The study population includes both simple and complex lesions, in patients with stable and acute coronary syndrome. The follow-up continues for 5years. The primary end point of the trial is target vessel failure, defined as the composite of cardiac death, myocardial infarction, and target vessel revascularization, at 2years. This study is registered on ClinicalTrials.gov with number NCT01858077.ConclusionThe AIDA trial will provide the first randomized direct comparison between the everolimus-eluting bioresorbable vascular scaffold and the everolimus-eluting metallic stent in contemporary percutaneous coronary intervention practice.© 2014.

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