• Curr Pain Headache Rep · Jul 2019

    Review

    Emerging Novel Pharmacological Non-opioid Therapies in Headache Management: a Comprehensive Review.

    • Alan David Kaye, Mark W Motejunas, Elyse M Cornett, Ken P Ehrhardt, Matthew B Novitch, Joshua Class, Harish Siddaiah, Brendon M Hart, and Richard D Urman.
    • Department of Anesthesiology, LSU Health Sciences Center, Room 656, 1542 Tulane Ave, New Orleans, LA, 70112, USA.
    • Curr Pain Headache Rep. 2019 Jul 8; 23 (8): 53.

    Purpose Of ReviewChronic headache is a significant worldwide problem despite advances in treatment options. Chronic headaches can have significant a detrimental impact on the activities of daily living.Recent FindingsPatients who do not obtain relief from chronic head and neck pain from conservative treatments are commonly being managed with interventional treatments. These interventional treatment options include botulinum toxin A, injections, local occipital nerve anesthetic and corticosteroid infiltration, occipital nerve subcutaneous stimulation and occipital nerve pulsed radiofrequency (PRF), sphenopalatine ganglion block, and radiofrequency techniques. Recently, evidence has emerged to support non-opioid-based drug and interventional approaches. Overall, more research is necessary to clarify the safety and efficacy of interventional treatments and to better understand the pathogenesis of chronic headache pain.

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