• World Neurosurg · Oct 2019

    Case Reports

    A Case of Hemorrhagic Moyamoya Disease Associated with Von Willebrand Disease.

    • Yume Suzuki, Masato Shiba, Hideo Wada, Ryuta Yasuda, Naoki Toma, and Hidenori Suzuki.
    • Department of Neurosurgery, Mie University Graduate School of Medicine, Tsu, Mie, Japan. Electronic address: box_308044@yahoo.co.jp.
    • World Neurosurg. 2019 Oct 1; 130: 335-338.

    BackgroundAssociation of moyamoya disease (MMD) with von Willebrand disease (vWD) is extremely rare.Case DescriptionWe first report a 27-year-old female case of MMD concurrent with vWD type 1, which presented as hemorrhagic stroke. The patient underwent a revascularization surgery with perioperative replacement therapy of von Willebrand factor and coagulation factor VIII. No hemorrhagic complications occurred.ConclusionsThe patient overcame postoperative transient neurological events and fully recovered. We discuss appropriate perioperative supplementation of coagulation factors for a revascularization surgery for MMD with vWD.Copyright © 2019 Elsevier Inc. All rights reserved.

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